Cardiac events in transfused lower IPSS risk MDS

  • Cardiac events included clinical episodes of CAD, CHF & ARR1
  • Median TTCE was 7 & 20 months for non-ICT & ICT patients1
  • In MVA, receiving ICT remained significant for TTCE (p=0.03)1
  • For a detailed discussion of the contribution of IOL to atherosclerosis, see Vinchi et al (2014)2

Figure Delayed time from RBC transfusion dependence to first cardiac event in lower IPSS risk MDS patients receiving iron chelation therapy

Chart - Cardiac Events - Time vs Cumulative Hazard